Giant Extracellular Matrix Binding Protein Expression in Staphylococcus epidermidis is Regulated by Biofilm Formation and Osmotic Pressure.

Authors: Linnes JC, Ma H, Bryers JD Abstract Staphylococcus epidermidis is an opportunistic bacterium that thrives as a commensal cutaneous organism and as a vascular pathogen. The S. epidermidis extracellular matrix binding protein (Embp) has been reported to be a virulence factor involved in colonization of medical device implants and subsequent biofilm formation. Here, we characterize the expression patterns of Embp in planktonic and biofilm cultures, as well as under high osmotic stresses that typify the commensal environment of the skin. Embp expression without osmotic stress was similar for planktonic and adherent cultures. Addition of osmotic stress via NaCl caused slight increases in embp expression in planktonic cultures. However, in adherent cultures a 100-fold increase i...







Pediatrician schedule: De Land, FL 27,257
Pediatrician schedule: Deerfield Beach 69,144
Pediatrician schedule: Delray Beach 64,691
Pediatrician schedule: Deltona 83,530
Pediatrician schedule: Destin 12,641
Pediatrician schedule: Doctor Phillips 11,275
Pediatrician schedule: Doral 31,389
Pediatrician schedule: Dowling Park 7,604
Pediatrician schedule: Dunedin 35,920
Pediatrician schedule: East Lake 29,091
Pediatrician schedule: East Lake-Orient Park 6,207
Pediatrician schedule: East Leon 31,203
Pediatrician schedule: East Marion, FL 23,131
Pediatrician schedule: East Orange, FL 14,372
Pediatrician schedule: East Perrine 7,689
Pediatrician schedule: East Wakulla 23,096
Pediatrician schedule: Edgewater, FL 21,225
Pediatrician schedule: Eglin 12,450
Pediatrician schedule: Eglin AFB 8,552
Pediatrician schedule: Egypt Lake-Leto 38,227
Pediatrician schedule: Elfers 17,414
Pediatrician schedule: Englewood, FL 18,266
Pediatrician schedule: Ensley 19,247
Pediatrician schedule: Estero 12,528
Pediatrician schedule: Estero Island 11,528
Pediatrician schedule: Eustis, FL 19,124
Pediatrician schedule: Fairview Shores 16,412
Pediatrician schedule: Fellowship 22,788
Pediatrician schedule: Fern Park 9,251
Pediatrician schedule: Fernandina Beach 11,636
Pediatrician schedule: Ferry Pass 27,894
Pediatrician schedule: Florida City 10,568
Pediatrician schedule: Florida Ridge 17,827
Pediatrician schedule: Forest City, FL 14,028
Pediatrician schedule: Fort Lauderdale, FL 163,160
Pediatrician schedule: Fort McCoy-Anthony 20,434
Pediatrician schedule: Fort Myers 64,674
Pediatrician schedule: Fort Myers Beach 6,325
Pediatrician schedule: Fort Myers Shores 7,637
Pediatrician schedule: Fort Pierce 42,596
Pediatrician schedule: Fort Pierce North 9,945
Pediatrician schedule: Fort Walton Beach 18,585
Pediatrician schedule: Fountainbleau 64,684
Pediatrician schedule: Fruit Cove 22,707
Pediatrician schedule: Fruitville 14,369
Pediatrician schedule: Fussels Corner 6,277
Pediatrician schedule: Gainesville, FL 104,875
Pediatrician schedule: Gibsonton 10,205
Pediatrician schedule: Gifford, FL 8,902
Pediatrician schedule: Glades 21,290


Federal Register: Agency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Medical Device User Fee Cover Sheet, Form FDA 3601
Class I Medical Device Recall: St. Jude Medical, AMPLATZER TorqVue FX Delivery System
PMA Final Decisions for December 2012
Pharmaceuticals and Medical Devices Agency (PMDA)'s New Action for Pharmaceutical Affairs Consultation on Research and Development (R&D) Strategy.
Nanoscale Vehicle Created To Battle Cancer Without Harming Healthy Cells
Class I Medical Device Recall: Vycor Medical, Inc., Vycor Viewsite Brain Access System (VBAS)
Kraton Performance Polymers To Showcase Cariflex™ Polyisoprene Products, The Super Clean Polyisoprene Polymer And Latex For High Performance Medical Devices, MEDTEC Europe, Stuttgart, Germany February 26-28, 2013
Is Innovation In Chromatography Losing Steam?
Molecular Imaging-based Early-Phase and Exploratory Clinical Research.
Mobile, Fast, Low-Cost Device Uses The Cloud To Speed Up Diagnostic Testing For HIV And More